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Does Bacteria in Gut Microbiota Protect Against Rotavirus?

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According to new research, Gut microbiota might play a major function in the prevention or cure of rotavirus (RV) infection. It is observed that a colony of mice was resistant to Rotavirus. This resistance shows attributable to one particular bacterial species called SFB or segmented filamentous bacteria . It is noticed that specific mice bred didn’t shed RV antigens. With the help of a fecal transplant, the transfer of rotavirus resistance was done and co-housing also transferred the resistance. Two strains of bacteria were isolated—SFB-G and SFB-P—determining that RV resistance associated with SFB-G was stronger. The presence of microbiota in the mice administered SFB-G affected the extent of the RV protection, indicating that other microbes play a role in resistance, maybe by supporting SFB colonization. SFB administration decreased RV shedding and also reduced the incidence of RV-induced diarrhea in compactly raised immunocompetent neonatal mice . This observation