Does Bacteria in Gut Microbiota Protect Against Rotavirus?

According to new research, Gut microbiota might play a major function in the prevention or cure of rotavirus (RV) infection.

It is observed that a colony of mice was resistant to Rotavirus. This resistance shows attributable to one particular bacterial species called SFB or segmented filamentous bacteria.

It is noticed that specific mice bred didn’t shed RV antigens. With the help of a fecal transplant, the transfer of rotavirus resistance was done and co-housing also transferred the resistance. Two strains of bacteria were isolated—SFB-G and SFB-P—determining that RV resistance associated with SFB-G was stronger. The presence of microbiota in the mice administered SFB-G affected the extent of the RV protection, indicating that other microbes play a role in resistance, maybe by supporting SFB colonization.

SFB administration decreased RV shedding and also reduced the incidence of RV-induced diarrhea in compactly raised immunocompetent neonatal mice. This observation gives a foundation for the improvement of new approaches to prevent and cure RV infection. However, since SFB promote the development of Th17 cells, which is associated with, and may intensify, chronic inflammatory diseases and those approaches should be considered with caution. The theory also noted that SFB is generally found among the gut bacteria of children in China, where RV infection is comparatively less severe.

https://bacterialdiseases.infectiousconferences.com/
Investigators also examined mechanisms that allow SFB to stop RV infection, with chances of including that the bacteria will give effect on RV directly or on the intestinal epithelial cells in which the RV binds. The study determined that SFB increased epithelial cell turnover, impeding RV.
Rotavirus is a highly transmittable cause of diarrhea worldwide, which causes very severe, life-threatening disease in some people and mild disease in some other people. Rotavirus infections kill an estimated 215,000 children younger than 5 each year.

A recent study determined that the virus can be transmitted in clusters inside vesicles in stool, which can travel through the gastrointestinal tract intact and they are more infectious than the individual viruses. A vaccine is used for the prevention of rotavirus infection, but there are currently no other treatments for the disease. Another recent study determined the vaccine to be very effective, conferring a 94% lower rate of hospitalization for rotavirus infections and a 31% lower rate of hospitalization for any other reason in the first 2 months after vaccination. The vaccine also has been linked to a lower risk of type 1 diabetes.

Comments

  1. RaymondAugust 10, 2020 at 4:40 AM

    Herpes is a serious and recurring disease which can't be cured through drugs or injections by the doctors but the best way to deal with Herpes is by taking natural herbs medicine for it,  I have read about DR NOGADU the great herbalist doctor who cure me from herpes  with his powerful herbal medicine.  i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! After 2 days of contacting him, he told me that the cure has been ready and he sent it to me via UPS SPEED POST and it got to me after 3 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! It was really like a dream but i was  so happy! you should contact him for his herbal medicine because i am a living testimony and i was cured of herpes and his medicine is legit.  I sent him what he requested and he sent me his medicine which I took for 2 good weeks and today I am out here with a negative result. When I went for the test I was so happy after going through his medication. you can reach him through his email: drnogaduherbalist@gmail.com or call/whatsapp number:+2347010627760 he will help you out.

    ReplyDelete

Post a Comment

Popular posts from this blog

Is Habitat Hotspots effective for Transmission of Diseases?

Image
Habitat Hotspots: The un-fold of infectious diseases powerfully depends on however habitat characteristics form patterns of between-host interactions. Specifically, habitat heterogeneousness influences patterns of between-individual contacts and thus, illness dynamics. For instance, “ habitat hotspots ”, sites that attract people or social teams over long distances, may be visited by an outsized set of a population. Around hotspots, between-individual contact rates typically increase in frequency, which amplifies disease transmission . In humans, faculties and dealing places are typical samples of hotspots and are shown to accelerate the un-fold of measles, influenza , and SARS. Thus, limiting transmission at hotspots has become a promising strategy for mitigating epidemics (e.g., influenza) though the potency of such methods additionally depends on the role hotspots play relative to alternative sources of local transmission (e.g., influenza). The un-fold of infectious disea
Read more

Is Pneumonia a deadly disease?

Image
Pneumonia is essentially a lung infection that can be serious and life-threatening. The infection can be viral, bacterial or fungal. It causes inflammation in the lungs, wherein alveoli or tiny air sacs inside the lungs get filled with liquid. The key to treating pneumonia and prevent it from getting fatal is early diagnosis and a relatively strong immune system . However, it has to be noted that young children who are weak because of malnutrition are the ones most hit by pneumonia. Pneumonia kills more infants than measles, diarrhea, and malaria combined. Pneumonia has four stages, namely consolidation, red hepatization , grey hepatization and resolution. Symptoms of pneumonia The first symptoms of pneumonia are the same as cold or flu. This is followed by high fever, sputum, chills, and cough. The infection ends in rusty or green phlegm, shortness of breath, chest pain which worsens with taking deep breaths, fatigue and weakness, shortness of breath,
Read more

Avian Influenza-An insight

Image
Avian flu refers to a group of infectious diseases caused by influenza viruses that infect birds causing disease. One sub type of Avian Flu is H5N1.  H5N1 is a severe infection with a high mortality rate.The first outbreak  of H5N1 bird  flu  was in December 2003. Since then, over 700 cases have been reported, in Africa, Asia, and Europe with the highest cases reported in Indonesia, Vietnam, and Egypt. The most recent  case of H5N1 was reported in Malaysia in March 2017. It killed a number of chickens, but no human cases were reported. It is not easy for humans to catch it, but it is fatal in 60 percentage  of cases. Symptoms include blood in the sputum, fever, headache  and an upset stomach . Deterioration can be rapid. Antiviral medication can help increase the chances of survival and reduce the impact of the disease. A pandemic is unlikely unless the disease learns to spread between people. What is H5N1?  Type  A strains of the influenza  virus cause H5N1 avian flu.  H5N1 a
Read more